CRISPR User By Scientists To Eliminate HIV From Mice


In history, for the foremost instance, HIV has been removed successfully by scientists from infected mice DNA. Scientists, in a study issued in Nature Communications, reported a probable new means to cure HIV, a condition that impacts a projected 1.1 million individuals in the US.HIV is a virus that hits the immune system of the body. This can make an individual more vulnerable to becoming unwell, and if it is not treated in time, HIV can transform into AIDS.

Researchers at the University of Nebraska Medical Center and the Temple University utilized a blend of CRISPR gene-editing tech and a therapeutic treatment known as “LASER ART” (long-acting slow-effective release antiviral therapy) to eliminate the HIV DNA from animals’ genomes. CRISPR-Cas9, which is a gene editing tool, has been called a groundbreaking methodology, as it has the likelihood of treating genetic diseases. Particularly, CRISPR supposedly provides the researchers with the ability to modify the DNA of a life form, an eventual aim of medical study for decades. LASER ART was utilized to maintain the virus’ replication at low levels for a lengthy period of time.

From the 21 mice that were assessed with the technology, 9 did not observe the return of the virus. The findings demonstrate altering the genes of the infected organism can be the solution for a cure. Now the CRISPR-LASER ART blend is being validated on non-human primates.

Likewise, a large clinical research study performed in 4 African countries observed no noteworthy difference in HIV infection threat among women utilizing one of 3 highly effectual, reversible contraceptive methods. The study, issued in the Lancet, demonstrated that every method had elevated levels of effectiveness and safety in thwarting pregnancy, with all techniques well-accepted by the females utilizing them. The 3 methods examined in the study were DMPA, Levonorgestrel implant, and a copper-bearing IUD.

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